The Week 4 NFL running back prop market has several opportunities worth targeting on the lower side. Ollie Gordon II faces a difficult Minnesota run defense, while Chase Brown draws a tough matchup against Jacksonville. Jonathan Taylor’s early-season efficiency has also dipped ahead of a challenging matchup with Washington.
If you’re looking for the best NFL running back props to bet in Week 4, these three picks feature difficult matchups, workload concerns and some appealing numbers to attack.
All odds are from DraftKings Sportsbook and are subject to change. DraftKings does not sponsor this content.
Best NFL RB Prop Bets for Week 4
Miami Dolphins RB Ollie Gordon II Under 24.5 Rushing Yards (-111)
Gordon faces a difficult matchup against a Minnesota defense that ranks second in opponent rush EPA and rush success rate. Gordon managed just 41 yards on 17 carries against Kansas City last week, averaging 2.4 yards per attempt. Jaylen Wright’s expected return could also cut into his workload. With Miami struggling to sustain drives and potentially playing from behind, Gordon may not see enough carries to make much of an impact on the ground.
Cincinnati Bengals RB Chase Brown Under 62.5 Rushing Yards (-111)
Brown has been held to 56 and 61 rushing yards in two of his first three games and now faces a difficult Jacksonville run defense. The Jaguars rank fifth in run-defense DVOA and have limited opposing running backs to 18.3 carries per game at just 3.2 yards per attempt. Brown is averaging 4.0 yards per carry with limited explosive plays, so he could need a heavier workload than usual to produce a big afternoon.
Indianapolis Colts RB Jonathan Taylor Under 90.5 Rushing Yards (-110)
Taylor is averaging just 3.9 yards per carry through three games, a full yard below his 2025 average. He also managed only 68 rushing yards against Houston last week and now faces another difficult matchup. Washington is allowing just 3.8 yards per carry while ranking third in opponent rush EPA and sixth in rush success rate. With his efficiency down and the Commanders defending the run well, Taylor could need a heavy workload to produce a big afternoon.
