MLB Home Run Predictions Today: HR Prop Bets for Monday, June 29

Target Brandon Lowe, Willson Contreras and Manny Machado as Monday's top MLB home run prop bets in premium power matchups.

by Athlon Sports
MLB Home Run Predictions Today: HR Prop Bets for Monday, June 29

Boston Red Sox first baseman Willson Contreras (40) hits a home run

Bob DeChiara-Imagn Images

Monday's "Moonshot Matchups" feature three hitters in outstanding spots to leave the yard. Brandon Lowe gets a struggling Aaron Nola, who has been giving up home runs in bunches, while Lowe continues to mash right-handed pitching. Willson Contreras welcomes Miles Mikolas to Fenway, where his strong history against the veteran righty makes this an intriguing matchup. Meanwhile, Manny Machado draws Shota Imanaga, one of baseball's most homer-prone pitchers, and has already taken him deep twice.

If you're looking for Monday's best home run props, these three sluggers have all the ingredients for a trip around the bases.

All odds are from DraftKings Sportsbook and are subject to change. DraftKings does not sponsor this content.

More MLB predictions:

  • Best MLB Player Prop Bet Predictions for Monday, June 29
  • Best First Inning Run Projection Predictions for Monday, June 29

Best Home Run Props Today

Brandon Lowe Home Run Bet (+266)

Lowe is swinging one of the hottest bats in baseball, and Monday's matchup is too good to pass up. Six of his 20 home runs have come in June, and 16 of those 20 blasts have come against right-handed pitchers like Aaron Nola. Lowe also owns a homer in just seven career at-bats against Nola, who has allowed six home runs over his last three starts.

Willson Contreras Home Run Bet (+356)

Contreras has a juicy matchup coming to Fenway on Monday against Miles Mikolas. The Red Sox slugger is 7-for-19 against the veteran right-hander with two doubles and a home run, and 12 of his 17 homers this season have come against righties. Mikolas has allowed 16 long balls this year, including five over his last five starts. Everything lines up for Contreras to leave the yard again Monday.

Manny Machado Home Run Bet(+253)

Machado is staring at one of the best home run matchups on Monday's board. Shota Imanaga has already surrendered 20 home runs this season—tied for the third most in baseball—and seven have come over his last four starts. Right-handed hitters have done most of the damage, and Machado has already taken Imanaga deep twice despite just 11 career at-bats against him.

2026 MLB HR Leaders

  • DH Kyle Schwarber, Philadelphia Phillies (30)
  • OF Yordan Alvarez, Houston Astros (25)
  • OF Byron Buxton, Minnesota Twins (25)
  • C Hunter Goodman, Colorado Rockies (25)
  • 1B Ben Rice, New York Yankees (22)
  • 3B Junior Caminero, Tampa Bay Rays (22)
Published:
by Athlon Sports

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