MLB Home Run Predictions Today: Best HR Prop Bets for Tuesday, Aug. 25

Tuesday’s MLB home run card puts Daulton Varsho, Mike Trout and Dominic Canzone in prime spots to send baseballs into the seats.

by Andrew Phelps

Aug 25, 2026

Los Angeles Angels center fielder Mike Trout (27) reacts to flying out

William Navarro-Imagn Images

It’s the “Tuesday Tater Tracker,” and three power bats have matchups ready for fireworks. Daulton Varsho gets Will Warren, a pitcher he’s already taken deep twice and who’s allowed four homers over his last two starts. Mike Trout draws Gavin Williams, whom he homered against in their only previous meeting. Meanwhile, Dominic Canzone faces Aaron Nola, who’s surrendered at least one bomb in eight straight starts.

If you’re looking for Tuesday’s best home run props, Varsho, Trout and Canzone have the matchup history, splits and power potential to leave the yard.

All odds are from DraftKings Sportsbook and are subject to change. DraftKings does not sponsor this content.

More MLB predictions:

Best First-Inning Run Projection Predictions for Tuesday, Aug. 25

Best Home Run Props Today

Daulton Varsho Home Run Bet (+TBD)

Varsho has brought some fresh thunder to Houston, already launching two homers since joining the Astros on Aug. 3. Now he gets Will Warren, a pitcher he’s absolutely torched, going 4-for-5 with two career bombs against him. Warren has been handing out souvenirs lately with four homers allowed over his last two starts, including 11 to lefties this season.

Mike Trout Home Run Bet (+451)

Trout may not be launching baseballs at his usual ridiculous pace, but Tuesday’s matchup has wake-up call written all over it. He’s crushed 15 of his 20 homers against righties and already took Gavin Williams deep in their only meeting. Williams has been serving up souvenirs all season, including four over his last three starts.

Dominic Canzone Home Run Bet(+TBD)

Nola takes the mound, so you already know I’m hunting for a home run. He’s allowed at least one bomb in eight straight starts, coughing up 12 during that stretch and 31 overall. Dominic Canzone has been quiet lately, but 15 of his 19 homers have come against righties. With Nola surrendering 18 bombs to lefties, I’m betting Canzone wakes up that power stroke with a Tuesday tater.