MLB Home Run Predictions Today: Best HR Prop Bets for Friday, Aug. 28

Vinnie Pasquantino, Kody Clemens and Pete Alonso headline Friday’s MLB home run predictions with favorable matchups and plenty of long-ball upside.

by Andrew Phelps

Aug 28, 2026

Kansas City Royals first baseman Vinnie Pasquantino (9) reacts after his fly ball

John E&period; Sokolowski-Imagn Images

It’s “Friday Fly Ball Frenzy,” and three power bats have matchups ready for some bleacher damage. Vinnie Pasquantino gets Tanner Bibee, whom he’s already taken deep twice and who’s allowed 20 homers to lefties. Kody Clemens draws Luis Castillo, a pitcher he’s already homered against. Meanwhile, Pete Alonso faces Jacob Lopez, who’s surrendered 13 of his 15 bombs to right-handed hitters.

If you’re looking for Friday’s best home run props, Pasquantino, Clemens and Alonso have the history, splits and power to send one into the seats.

All odds are from DraftKings Sportsbook and are subject to change. DraftKings does not sponsor this content.

Best MLB First-Inning Predictions (NRFI/YRFI) for Friday, Aug. 28

Best Home Run Props Today

Vinnie Pasquantino Home Run Bet (+380)

Pasquantino sees Tanner Bibee on Friday, and he might start smiling before he even reaches the batter’s box. He’s crushed the righty, going 10-for-17 with two homers in their previous meetings. Bibee has also become a launching pad lately, surrendering six bombs over his last four starts and 20 to lefties this season.

Kody Clemens Home Run Bet (+357)

Clemens has officially found the launch button this season, crushing a career-best 21 homers after never reaching 20 before. Sixteen have come against righties, and Friday brings a familiar target in Luis Castillo. Clemens has already taken him deep while going 2-for-5 in their matchups. Castillo has surrendered 14 bombs to lefties like Clemens this season.

Pete Alonso Home Run Bet (+204)

Alonso is putting baseballs on a frequent-flyer program, crushing nine homers this month and three in the last week. The Polar Bear is up to 32 bombs and has 40 squarely in his sights. Now he gets Jacob Lopez, a lefty he’s already taken deep once. Lopez has surrendered 13 of his 15 homers to righties, making this matchup way too tasty.