MLB Home Run Predictions Today: Best HR Prop Bets for Friday, Aug. 14

Alex Bregman, Jackson Merrill and Chase DeLauter headline Friday's MLB home run predictions with favorable matchups and plenty of power upside.

by Andrew Phelps

Aug 14, 2026

San Diego Padres center fielder Jackson Merrill (3) is congratulated after hitting a two-run home run

Denis Poroy-Imagn Images

It's "Friday Fly Ball Frenzy," and three power bats have juicy matchups to attack. Alex Bregman brings a four-homer heater into a matchup with Matthew Liberatore, a pitcher he's already taken deep. Jackson Merrill gets Gavin Williams, who's surrendered seven homers over his last seven starts. Meanwhile, Chase DeLauter draws Michael King, who's allowed most of his home runs to left-handed hitters.

If you're looking for Friday's best home run props, Bregman, Merrill and DeLauter have the power, splits and matchups to leave the yard.

All odds are from DraftKings Sportsbook and are subject to change. DraftKings does not sponsor this content.

Best MLB First-Inning Predictions (NRFI/YRFI) for Friday, Aug. 14

Best Home Run Props Today

Alex Bregman Home Run Bet (+580)

Bregman is seeing beach balls right now, crushing four homers over his last three games to push his season total to 16. Now he gets Matthew Liberatore, a pitcher he's already taken deep while going 3-for-7 with three extra-base hits against him. Liberatore has served up 20 bombs this season, including 13 to right-handed hitters.

Jackson Merrill Home Run Bet (+484)

Merrill is knocking on the door of a career-best power season, sitting at 19 homers with six needed to set a new high. The lefty has crushed right-handed pitching for 16 of those bombs while carrying a strong 47% hard-hit rate. Gavin Williams has been handing out souvenirs lately, allowing seven homers over his last seven starts and 13 to lefties this season.

Chase DeLauter Home Run Bet (+553)

DeLauter has plenty of thunder in that left-handed bat, crushing 13 homers despite missing a chunk of June. Eleven of those bombs have come against righties, backed by a strong 46.3% hard-hit rate. Enter Michael King, who's surrendered nine of his 15 home runs to left-handed hitters and four over his last three starts.