MLB Opening Day is right around the corner, and there’s no better time to lock in some futures before the season gets rolling. It’s one of the best betting opportunities on the calendar, with plenty of value still on the board.
This article highlights six season-long bets worth targeting—including a potential AL winner out of Detroit, Cy Young picks in both leagues, a Rookie of the Year candidate from Baltimore, a Boston star ready for a big season, and a Chicago closer who could dominate late innings.
All odds are from DraftKings Sportsbook and are subject to change. DraftKings does not sponsor this content.
Detroit Tigers +900 to Win the American League
Detroit’s elite rotation, led by Tarik Skubal and boosted by Framber Valdez and Justin Verlander, gives them a real edge. The pitching can carry this team, and the bullpen is deeper than ever. Pair that with a young core continuing to improve, and there’s a strong foundation here. If things come together, the Tigers have a legit shot to win the American League at a great price.
Bob DeChiara-Imagn Images
Roman Anthony +1400 to Win AL MVP Award
Anthony brings a rare mix of elite bat speed and power-contact ability, and when he elevates the ball, it jumps. After a strong rookie showing and a big WBC performance, the breakout potential is real. If he trims the ground-ball rate even slightly, the numbers could explode, and playing in Boston gives him the spotlight needed to make a real MVP run.
Daniel Palencia +2500 to Most Regular Season Saves in MLB
Palencia brings elite, triple-digit velocity and a wipeout slider, giving him closer stuff that’s tough to hit. He already piled up 22 saves in 54 appearances last year and now has full control of the ninth inning. If the Cubs win the division, the opportunities will be there. With his strikeout ability and defined role, he has a strong path to finishing with the most saves.
Jacob deGrom +1300 to Win AL Cy Young Award
He proved last season he can stay healthy and handle a full workload again, posting a sub-1 WHIP with strong strikeout numbers. His stuff is trending back toward peak form, and the dominance is still there. If he builds on that with another full season, his mix of efficiency and strikeouts puts him firmly in the Cy Young conversation.
Jayne Kamin-Oncea-Imagn Images
Jacob Misiorowski +3000 to Win NL Cy Young Award
Misiorowski brings elite, triple-digit velocity and a nasty mid-90s slider that keeps everything in sync. The biggest key is command, and he showed real progress late last season. If that continues, his combination of power stuff and improving consistency gives him the upside to dominate and emerge as a serious NL Cy Young contender.
Samuel Basallo +1100 to Win AL Rookie of the Year Award
Basallo brings elite power and top-tier prospect upside, with 20+ homer potential and some of the hardest contact in the minors. The Orioles will keep his bat in the lineup across multiple positions, giving him plenty of at-bats. After a brief MLB stint, he’s set for a bigger role, and if it clicks, the production could be big enough to put him right in the Rookie of the Year mix.
