Final Injury Report for Texans-Colts: Will Nico Collins, Alec Pierce Play?

Both the Houston Texans and Indianapolis Colts may be without multiple key players in Sunday afternoon’s matchup.

by Nathaniel Holloway

Sep 27, 2026

Houston Texans wide receiver Nico Collins (12) celebrates after a reception during the second quarter against the Tennessee Titans at NRG Stadium.

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The Houston Texans are on the road Sunday afternoon as they travel to take on the Indianapolis Colts in a Week 3 AFC South showdown.

Houston enters Sunday’s game with an 0-2 record after losing at home to the Cincinnati Bengals in Week 2.

Houston Texans quarterback C.J. Stroud (7)

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In their loss to the Bengals, C.J. Stroud led the way for the Texans as he recorded 353 passing yards while Dalton Schultz added 140 receiving yards.

The Texans will try to bounce back and grab their first victory of the season Sunday as they face off against the Colts in a tough road matchup.

Indianapolis enters Sunday’s contest with an 0-2 record after losing on the road in overtime to the Kansas City Chiefs in Week 2.

Indianapolis Colts running back Jonathan Taylor

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Jonathan Taylor led the way for the Colts in their loss to the Chiefs as he ended the game with 132 total yards and two rushing touchdowns while Daniel Jones recorded 210 passing yards, one passing touchdown and an interception.

While both teams are looking to pick up a victory in Sunday afternoon’s matchup, each may be without multiple key players due to injuries.

Texans Injury Report: Will Nico Collins, Trent Brown Play?

Houston Texans wide receiver Nico Collins (12)

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The Texans have six players listed on their injury report, including wide receiver Nico Collins and offensive lineman Trent Brown.

Houston has ruled out Collins due to a hamstring injury as he will miss his second consecutive contest.

With Collins sidelined, Kayshon Boutte, Xavier Hutchinson and Dalton Schultz could all continue to have increased roles.

The Texans have listed Brown as questionable due to knee and wrist injuries and he is in danger of missing his first game of the season.

Houston Texans offensive tackle Trent Brown

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Safety M.J. Stewart (knee), linebacker Jake Hummel (groin), guard Ed Ingram (groin) and linebacker Jadeveon Clowney (knee) have all been ruled out.

Colts Injury Report: Will Alec Pierce Play?

Indianapolis Colts wide receiver Alec Pierce (14)

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The Colts have three players listed on their injury report, including wide receiver Alec Pierce.

Indianapolis has ruled out Pierce due to a heel injury that he reaggravated in Week 2 and he is expected to miss multiple weeks.

The Colts have also ruled out wide receiver Ashton Dulin due to an ankle injury while cornerback Charvarius Ward Sr. is questionable with a groin injury.

Fans can catch Sunday afternoon’s matchup between the Texans and Colts from Lucas Oil Stadium at 1 p.m. ET on CBS in both teams’ home markets and select other locations across the country. Check local listings for games available in your area.